Under physiological conditions, the glomerular capillary wall can effectively prevent macromolecular materials in the blood, such as protein and red blood cells into the kidney capsule. While the pathological condition, the filter barrier is destroyed, and there will be glomerular proteinuria.
Nephropathy syndrome factors include their own system defects, living environment, genetic and other factors, cellular immune system and immune mechanism.
Effect of cyclosporine on the treatment of nephrotic syndrome.
Immune mechanism. Cyclosporine inhibits the activation selectivity and reversibility of IL-2 and T lymphocytes
Non - immune mechanism. It can help reduce proteinuria by affecting glomerular permeability, including aperture selection, charge selectivity and glomerular filtration rate (GFR).
The main function of podocytes is to maintain the normal function of glomerular filtration through the barrier. Synaptophysin is one of the major proteins in podocytes, and cyclosporine can help to help podocyte stability and reduce loss.
Cyclosporins can effectively reduce proteinuria and inflammation in the body, but long-term cyclosporine can cause a lot of side effects, such as full moon face, low immunity, osteoporosis, femoral head necrosis.
Micro-penetration of traditional Chinese medicine can not only help patients to eliminate proteinuria, but also to help patients improve renal function. This is a topical therapy, in this therapy, the main raw materials were crushed into powder, the main raw material of the active substance can direct lesions, in order to achieve anti-inflammatory, anticoagulant, anti-inflammatory, the purpose of degradation.
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