Nephrotic syndrome, how much do you know?

 What is nephrotic syndrome?
Nephrotic syndrome is a large number of proteinuria (adults> 3.5 g / day, children> 50 mg / kg body weight / day), hypoalbuminemia (≤ 30 g / l), edema, hyperlipidemia and lipid For a group of clinically manifested diseases. These manifestations directly or indirectly increase the permeability of the glomerular filtration membrane (like the "screen" of the mesh becomes larger) to the plasma protein leakage, a large number of protein loss from the urine related. Therefore, a large number of proteinuria and hypoalbuminemia is a necessary condition for the diagnosis of nephrotic syndrome. Edema can be very serious, can also be lighter or not obvious. Some patients may not be high blood lipids, especially secondary nephrotic syndrome. Therefore, hyperlipidemia and edema is not a necessary condition for the diagnosis of nephrotic syndrome.

What Are the Causes of Relapse in Nephrotic Syndrome

What causes the cause of nephrotic syndrome?
According to the cause can be divided into primary and secondary two categories. There are many causes of secondary nephrotic syndrome, children with hereditary diseases, infection (streptococcal infection after nephritis), allergic purpura more common; young patients with systemic lupus erythematosus (especially women), infection, drug factors; The elderly were diabetic nephropathy, renal amyloidosis, multiple myeloma and more common. At least half of patients with nephrotic syndrome have a definite secondary cause. Primary, refers to the original lesion occurs in the glomerular disease. Various types of primary glomerular diseases, such as acute nephritis, acute nephritis, chronic nephritis and glomerulonephritis, can occur in the course of disease nephrotic syndrome. In the pathological classification, mainly including minor lesions kidney disease, mesangial proliferative glomerulonephritis, membranous nephropathy, membranoproliferative glomerulonephritis and focal segmental sclerosis. In children about 80% is caused by minor lesions of kidney disease; in adults, foreign reports to membranous nephropathy more common, but our most common mesangial proliferative glomerulonephritis.
Why is Nephrotic Syndrome Easy to Relapse

What are the clinical manifestations of nephrotic syndrome?
Proteinuria some patients can be asymptomatic, due to urine routine examination and found. Urine protein to ++++, 24 hours urine protein> 3.5 grams, some cases can be combined with hematuria.
Chinese Therapy for Relieving Swelling for Nephrotic Syndrome Patients

Hypoalbuminemia nephrotic syndrome is generally manifested as hypoproteinemia, serum albumin ≤ 30 g / l. But a large number of proteinuria and hypoalbuminemia is not completely consistent. In addition, there can be globulin, transporter, coagulation fibrinolytic protein changes.
Hyperlipidemia and Lipid Urine Most patients with nephrotic syndrome in patients with total cholesterol, phospholipids and triglycerides increased urine urine urine can occur.
What Causes Hyperlipidemia in Nephropatic Syndrome

Edema and edema often appear, initially more common in the ankle, according to the depression; morning when the eyelid edema, gradually and the body; severe ascites, pleural effusion or pericardial effusion. Edema is not serious, only the performance of weight gain.
Hypertension of about 1/3 of patients with nephrotic syndrome can occur in hypertension, edema, about half of those who have high blood pressure, blood pressure often 140-170 / 95-110 mm Hg.
How To Treat Nephrotic Syndrome Without Making It Relapse

Major complications are secondary to infection, the most common is respiratory infections, urinary tract infections, skin infections and peritonitis. Insufficient blood volume in patients with orthostatic hypotension. Pediatric children due to edema was prone to heart failure, elderly patients easily complicated with acute renal failure. Most patients with nephrotic syndrome are in hypercoagulable state and have a tendency to form thrombus and embolism.
What is the progress of research on nephrotic syndrome?
Nephrotic syndrome treatment, one for the cause of treatment, the second is the treatment of complications (such as edema, hyperlipidemia), the third is the treatment of proteinuria, but can not simply eliminate or reduce proteinuria for the sole purpose. Although some cases, although strict and regular treatment, proteinuria is still unable to control, and renal function was significantly reduced, the treatment of these refractory nephrotic syndrome should be turned to protect renal function.

What Does Nephrotic Syndrome Patient Need on Diet

 

Kidney disease is one of the human health killers,no matter what is the causes, kidney disease has affected the normal life of patients gradually.In order to let everyone have a healthy body,I hope our medical group can do our best to help the kidney disease patients all over the world. If you want to get some treatment or diet suggestions for kidney problem, you can feel to contact me by E-mail renal-disease@hotmail.com,or WhatsApp / Phone:008613633219293.

Hope that the patients will be helpful!