Clinical manifestations of nephrotic syndrome

A large number of proteinuria. A large number of proteinuria is a sign of clinical manifestations of nephrotic syndrome, mainly due to glomerular basement membrane permeability changes, resulting in a large number of proteinuria, the main component is albumin, also contains other plasma protein components. In addition, changes in the charge barrier and mechanical barrier, renal tubular epithelial cell reabsorption and catabolic capacity can also cause proteinuria; glomerular filtration rate decreased, proteinuria will be reduced; severe hypoproteinemia , Urinary protein excretion is increased, therefore, want to measure proteinuria alone can not be judged by the daily measurement, should be albumin clearance rate.
Complications in Nephrotic Syndrome

Edema This should be the most annoying symptoms of the patient, because edema will not only make people feel uncomfortable, but also hinder the appearance of the performance of the gradual increase in systemic edema, early morning when the eyelid, facial, ankle edema, slowly Edema will spread to the body, there pleural effusion, ascites, pericardial effusion, scrotum, etc. can also occur pulmonary edema, the patient is relatively mild edema can still normal activities, but if it is serious patients, edema to even the eyes are also open Not open, head and neck thicker, the skin was waxy pale, by the chest, ascites and lead to breathing difficulties, to always sit, once the supine will aggravate the symptoms.

What Are the Common Symptoms in Nephrotic Syndrome

3. Hypoproteinemia. Patients with serum albumin per liter of less than 30 grams, the patient's liver albumin synthesis will be increased, when the liver synthesis of albumin compensatory effect is not enough to make up for the loss of urinary protein, the emergence of hypoproteinemia.
4. Hyperlipidemia. Hyperlipidemia and hypoalbuminemia, thrombosis and progressive glomerulosclerosis, the disease showed total cholesterol, triglyceride increased significantly, low density lipoprotein, very low density lipoprotein levels.

Diarrhea in Nephrotic Syndrome: Causes and Treatment
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