Chronic nephritis inheritance

Chronic nephritis slowly erodes human health and suffers from the lives of patients. Many patients suggest that chronic nephritis is such a genetic problem, chronic nephritis refers to proteinuria, hematuria, hypertension, edema as the basic clinical manifestations, different ways of onset, disease progression, slow progress of the disease, can be different degrees of renal dysfunction, Will eventually develop a group of glomerulopathy for chronic renal failure. Then chronic kidney disease will be passed to the next generation? To see the cause of the disease.

Clinical findings, only a small number of chronic nephritis is caused by the development of acute nephritis. Because most patients with chronic nephritis etiology is unclear, its pathogenesis and acute nephritis is similar to an autoimmune response process. Why the mechanism leading to chronic processes is unclear, may be associated with some of the body's immune function defects.

Chronic glomerulonephritis is not hereditary, not an independent disease, but only any primary or secondary glomerulonephritis in the stage of progress into the end stage of renal failure. At this time different types of glomerulonephritis pathology and clinical manifestations are consistent, there proteinuria, hematuria, edema, hypertension was irreversible, all end-stage renal failure cases, about 60% caused by chronic glomerulonephritis The

Chronic nephritis has a different genetic way, the most common way of a genetic and gender-related, that is, the mother's disease also pass the daughter, So most of the chronic nephritis is not hereditary, mostly caused by immune system dysfunction, part of the nephritis is a long time from the acute nephritis healing, extended more than a year conversion from.

Hereditary chronic nephritis - Alport syndrome. The age of this chronic nephritis earlier, 70% of patients before the onset of 10 years of age, early often no symptoms, mostly only asymptomatic proteinuria and persistent hematuria, the condition continued to slow progress, to be found when the condition has been more serious. Male patients than women in patients with mild condition, may have a normal life, but also can develop into uremia.

Hematuria is the most prominent clinical manifestations of chronic nephritis, all patients have microscopic hematuria or gross hematuria, chronic nephritis early generally no proteinuria, with the progress of the disease can gradually appear, proteinuria and high blood pressure at the same time, poor prognosis. Neurological deafness is another feature of this disease, male more common, deafness and more bilateral symmetry. 15% to 30% of patients will have eye lesions, including the lens and retinal diseases.

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