What are the disadvantages of hormone nephrotic syndrome?

 The application of glucocorticoids in nephrotic syndrome is an indispensable part of hormone therapy, the use of its treatment to a certain extent, ease the patient's pain and improve the short-term efficacy, but no control of hormone applications as if Opened the "Pandora's box", to bring happiness to people at the same time, also led to a disaster, so that patients have a variety of irreversible serious symptoms:

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1, long-term super physiological dose of glucocorticoid application can cause water, salt, sugar, protein and fat metabolism disorders, the emergence of adrenal cortical hyperthyroidism. Manifested as centripetal obesity, resulting in calcium absorption disorders, resulting in osteoporosis, severe cases can also occur spontaneous fracture.
2, glucocorticoid can reduce the body's ability to prevent disease, is conducive to the growth and proliferation of bacteria and proliferation, induced or aggravated infection.
3, glucocorticoid to promote protein decomposition, can delay the formation of granulation tissue, prevent trauma or surgical wound and other ulcer healing.
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4, glucocorticoid has the role of anti-growth hormone, children's long-term application can inhibit bone growth and protein synthesis, affecting growth and development, pregnant women can also cause fetal malformations.
5, long-term use of glucocorticoid therapy, in the basic control of symptoms, such as reductions too fast or sudden withdrawal, the original symptoms may appear rapidly or aggravated, known as the "rebound phenomenon." There are some symptoms of the original disease, such as myalgia, muscle rigidity, joint pain, said withdrawal symptoms (or withdrawal syndrome).
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In addition, long-term use of glucocorticoids can cause adrenal cortical atrophy or dysfunction, induced and aggravated ulcers and even cause neuropsychiatric symptoms, for patients with a great obstacle to rehabilitation.
In short, the treatment of hormones is only a mere formality, and did not solve the real problem, made a "headache, foot pain," the taboo, so the application of hormones must be appropriate, not blind pursuit of efficacy and a large number of hormones, Patients can not only stare at the test indicators, in the treatment direction into the errors.

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