Purpuric nephritis

Purpuric nephritis, also known as Henoch-Schonlein purpura nephritis, is Henoch-Schonlein Purpura, HSP, with necrotic vasculitis as the main pathological changes in systemic disease, can involve systemic multiple organs) when the kidney damage which performed. Clinical manifestations in addition to skin purpura, joint swelling and pain, abdominal pain, blood in the stool, the main hematuria and proteinuria, occurred in the skin after a month of purpura, some or can also see skin purpura, abdominal pain, Symptomatic urinary abnormalities.
What Are the Symptoms in Purpura Nephritis

According to the pathogenesis of allergic purpura for allergic reactions, there are two types of cases:
1, rapid onset of allergic reactions: allergens and in vivo protein binding, the formation of antigen. The resulting IgE antibody adsorbs on mast cells and releases histamine and slow response substances (SRS-A). Such substances cause small arteries and telangiectasia, increased vascular permeability.
2, the immune response: is due to the formation of antigen - antibody complex. This type of soluble, small molecule complexes can stimulate the release of histamine and serotonin from basophils, but also on the basement membrane of the vessel wall and glomeruli to activate the complement and cause tissue damage.

What are the Clinical Symptoms of Purpura Nephritis

What are the symptoms of purpura nephritis?
1, simple purpura generally no systemic symptoms, the two legs may appear scattered in the needle size of the red petals, the pressure does not fade. Seven days later the color gradually faded and subsided. But there are new petechiae.
2, idiopathic thrombocytopenic purpura can be divided into acute and chronic type two. Acute type is rare, can occur in children, often before the onset of infection history. The disease is characterized by sudden onset, fever, extensive skin bleeding, may have large ecchymosis, hematoma, and mucosal and genitourinary system bleeding, platelets were significantly reduced, less than 5,000 / mm3. Chronic type is more common, more young women, slow onset, for persistent or recurrent bleeding. Not only in the skin, mucous membranes or internal organs can also be severe bleeding.

Best and Effective Treatment for Purpura Nephritis

3, rheumatic purpura symptoms of two lower limbs appear slightly uplift size of the grain size of ecchymosis, can also occur petechiae, wind group or edema erythema. At the same time may have joint swelling and pain, but also may have fever, limb weakness and other systemic symptoms.
4, abdominal purpura skin performance with rheumatic purpura symptoms, but there may be abdominal pain, vomiting, diarrhea, tenesmus, stool bleeding and other symptoms, severe cases may be complicated by intussusception.

How to Stop Proteinuria in Purpura Nephritis Patients

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