diabetic nephropathy symptoms

1, proteinuria. Proteinuria is the first sign of diabetic nephropathy. Diabetic nephropathy early, urine only a small amount of albumin symptoms, selective proteinuria, this state can last for many years. With the progress of diabetic nephropathy, patients began to appear persistent proteinuria symptoms, glomerular filtration rate gradually decreased, the severity of kidney disease will be further aggravated. At this point, patients with diabetic nephropathy in a large number of proteinuria, glomerular filtration rate is lower than normal, the patient's progress in the deterioration of the kidneys will be difficult to control, and soon will develop into diabetic renal failure.
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2, edema and nephrotic syndrome. Early diabetic nephropathy patients generally no swelling; when diabetic patients with 24-hour urine protein quantification of more than 3 grams, the swelling will appear. Once the patient has obvious systemic swelling, the condition of diabetic nephropathy continued to progress. Diabetic nephropathy patients with physical edema symptoms more than half of the affected population, which may be due to diabetic patients suffering from kidney disease caused by loss of large amounts of protein caused by hypoproteinemia. Diabetic nephropathy in patients with longer duration, causing edema of diabetic nephropathy more complications, of which about 20% of diabetic patients with nephrotic syndrome.

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3, high blood pressure. Blood pressure is common in patients with diabetic nephropathy, which is a late symptom of diabetic nephropathy, the occurrence of persistent proteinuria longer diabetic nephropathy in patients with hypertension symptoms. In the early stage, patients with diabetic nephropathy only increase blood pressure after exercise; when persistent proteinuria occurs, blood pressure continues to increase. The emergence of high blood pressure will accelerate the progress of renal function in patients with diabetic nephropathy, so effective control of hypertension in patients with diabetic nephropathy is very important.
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4, renal failure. Once the diabetic kidney damage, the course of the disease is progressive, and ultimately develop into azotemia, uremia. Early stage of diabetic nephropathy, in order to adapt to the needs of the body's sugar, glomerular filtration rate increased blood urea nitrogen and creatinine levels normal. Once the body of persistent proteinuria, the patient's blood urea nitrogen and creatinine concentration will increase, resulting in renal dysfunction, this time without control, diabetic nephropathy in patients within a few years to develop uremia.

5, anemia. There are obvious azotemia in patients with diabetic nephropathy, may have mild to moderate anemia symptoms, with iron therapy is invalid. Anemia is caused by erythropoiesis, which may be associated with long-term restrictions on protein diets and azotemia in patients with diabetic nephropathy.
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6, other symptoms. With the progress of diabetic nephropathy, patients can occur retinal disease symptoms. Although diabetic retinopathy caused by non-diabetic nephropathy, but often with the presence of diabetic nephropathy. In addition, diabetic nephropathy often accompanied by a variety of complications symptoms: heart failure and cystitis and other complications of diabetic nephropathy often affect the patient's renal function; ketoacidosis and hyperosmolar coma with circulatory failure, diabetic nephropathy patients Acute renal failure.

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