Diabetic nephropathy is already one of the more common diseases. According to the relevant experts, causing diabetic nephropathy for many reasons, different patients with different treatment methods, we should be the early prevention and treatment of the disease.
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Other pathologic changes in diabetic nephropathy include glomerular basement membrane thickening, glomerular epithelial cell fossa fusion, and glomerular enlargement due to extracellular mesangial matrix. Late renal tubular atrophy may occur renal fibrosis.
Diabetes course of more than 10 years of about 50% of diabetic nephropathy, the annual increase in end-stage renal disease, the proportion of diabetes caused by increasing year by year.
So what is the treatment of diabetic nephropathy? We learned from the kidney hospital, the current medical terms, the treatment of diabetic nephropathy mainly in two aspects: the control of predisposing factors and DN development of key links in the block. Genetic improvement refers to the application of genetic engineering and molecular genetic principles, with exogenous genetic material to replace or antagonize a wrong gene in order to achieve the purpose of preventing or improving the disease, it can modify the special gene.
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The disease is currently type 1 diabetes, the main method is the use of insulin and islet transplantation, but the application of insulin can not prevent the disease and its cardiovascular complications;
Islet transplantation is due to the immune response eventually lead to islet loss, people try to type 1 diabetes genetic diagnosis, gene improvement is a hot topic in the field of modern medicine, compared with the treatment of drugs or recombinant proteins, theoretically have many advantages to improve the continuity , Can completely cure certain diseases, the resulting protein is more similar to the normal body of the protein, the production process is simple, low cost, have greater potential for development, is expected to become an important means of treatment of kidney disease.
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