How much creatinine is uremia

Under normal circumstances, creatinine may have serum creatinine and urinary creatinine, the normal value of creatinine, creatinine is the number of uremia, the evaluation of each hospital standard is not the same. Usually, the normal value of serum creatinine is: 40 ~ 120umol / l between, once more than that range, it shows that renal function problems. In addition, the normal value of male and female creatinine is not the same. Creatinine is the number of uremic period can be divided into four levels of serum creatinine. Let's take a look:

1, renal failure compensatory period:
Assuming that the whole renal function is 100% normal, then this period GFR is normal 35% to 70% (clinical common creatinine clearance to reflect the GFR). At this point the decline in the reserve capacity of the kidney, but the function of the kidney can still maintain the body environment stability, clinical asymptomatic and azotemia (ie, serum creatinine normal). It should be noted, however, that if the creatinine clearance rate is simply staged, there may be overlapping between periods. At this time the value of creatinine is: 133 ~ 177umol / l.
How much is creatinine uremia? Followed by the second stage of chronic renal failure, renal failure decompensation.

2, renal failure decompensation:
Also known as azotemia, referred to as renal failure, is a prelude to chronic renal failure. At this time the glomerular filtration rate reduced to normal 21% to 35%, renal maintenance of the body's ability to stabilize the environment has been some damage, may have varying degrees of azotemia, renal thickening function of mild damage (polyuria And nocturia), and may have mild anemia. Under normal circumstances, clinically no obvious symptoms, easily overlooked. At this time the value of creatinine is: 177? 442umol / l.
How much is creatinine uremia? We look at the third stage of chronic renal failure, renal failure, this time is more serious period, this time the serum creatinine has been up to 400umol / l or more.

3, renal failure period:
When the GFR reduced to normal 11% to 20%, the body's internal environment has been long and sustained abnormal, there is significant azotemia, anemia is also more obvious; concentrated function is clearly obstacles (such as urine, nocturia ), As well as water, electrolyte imbalance, such as mild or moderate metabolic acidosis, water retention, hypocalcemia, hyperphosphatemia, etc., generally no hyperkalemia. May have mild gastrointestinal, cardiovascular and central nervous system symptoms. At this time the value of creatinine is: 442? 707umol / l.
How much is creatinine uremia? It is the last stage, that is, uremia period. At this time the serum creatinine has been up to the end.

4, uremia period:
That is, the end of renal failure, when the renal failure of the further development of the remaining GFR only 10% of the normal, that is, uremia symptoms group, high creatinine, the performance of the renal failure of the clinical manifestations more clearly Severe systemic symptoms, especially gastrointestinal, cardiovascular and neurological symptoms more prominent. How much is creatinine? Uremic period is blood creatinine> 707umol / L, water, electrolyte serious imbalance, often obvious metabolic acidosis.

So, how much creatinine is uremia?
When the creatinine development to greater than 707umol / l, has been described as the end of uremia, this time, the patient's renal function has been basically completely damaged. So, once the creatinine exceeds the normal range, you need to actively and effective treatment, and wait until the development of uremic period, the treatment will be very difficult.

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