Nephrotic syndrome and genetic relationship exists, the relevant research shows that the family if the existence of nephrotic syndrome patients, the prevalence rate is higher than no family history, compatriots and twins in the incidence rate of 2% to 6%.
What Are the Causes of Relapse in Nephrotic Syndrome
Second, allergy
Related studies have shown that patients with nephrotic syndrome due to allergic onset accounted for 35.5%; also confirmed that some patients with nephrotic syndrome with eosinophilic granuloma, manifested as systemic edema, posterior lymph nodes, eosinophilic leukocyte levels Elevated, all proteinuria, hypoproteinemia and hyperlipidemia, serum IgE increased, the detection of patients with Candida albicans and diphtheria vaccine allergies and nephrotic syndrome.
The Prognosis of Nephrotic Syndrome
Third, immune abnormalities
Nephrotic syndrome is associated with humoral immunity, immune complex formation, and cellular immune abnormalities. It has been reported that serum C3 and C4 decreased, ASO and ASK increased in patients with nephrotic syndrome complicated with hemolytic uremic syndrome. The serum antibodies of EFLO3 were increased. Kidney biopsy under the computer to see fibrin-like material, subcutaneous electron dense material calm, some subcutaneous electron dense matter calm. Immunofluorescence antibody examination see IgG, IgA, IgM, C1q, C3, fibrin deposition. These changes impair kidney function and can lead to nephrotic syndrome.
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